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A Phase II Evaluation of AMG 102 (Rilotumumab) In The Treatment Of Persistent Or Recurrent Epithelial Ovarian, Fallopian Tube Or Primary Peritoneal Carcinoma: A Gynecologic Oncology Group Study

PURPOSE: This open-label, multi-institutional Phase II trial evaluated activity and safety of rilotumumab (AMG 102), a monoclonal antibody that targets HGF (hepatocyte growth factor), the ligand for the MET receptor, in women with recurrent or persistent epithelial ovarian, fallopian tube or primary...

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Detalhes bibliográficos
Publicado no:Gynecol Oncol
Main Authors: Martin, Lainie P., Sill, Michael, Shahin, Mark S., Powell, Matthew, DiSilvestro, Paul, Landrum, Lisa M., Gaillard, Stephanie L., Goodheart, Michael J., Hoffman, James, Schilder, Russell J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469031/
https://ncbi.nlm.nih.gov/pubmed/24361733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2013.12.018
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