Airway bacteria measured by quantitative polymerase chain reaction and culture in patients with stable COPD: relationship with neutrophilic airway inflammation, exacerbation frequency, and lung function

BACKGROUND: Potentially pathogenic microorganisms can be detected by quantitative real-time polymerase chain reaction (qPCR) in sputum from patients with COPD, although how this technique relates to culture and clinical measures of disease is unclear. We used cross-sectional and longitudinal data to...

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Vydáno v:Int J Chron Obstruct Pulmon Dis
Hlavní autoři: Bafadhel, Mona, Haldar, Koirobi, Barker, Bethan, Patel, Hemu, Mistry, Vijay, Barer, Michael R, Pavord, Ian D, Brightling, Christopher E
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468933/
https://ncbi.nlm.nih.gov/pubmed/26089657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S80091
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