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Structural insights into the translational infidelity mechanism

The decoding of mRNA on the ribosome is the least accurate process during genetic information transfer. Here we propose a unified decoding mechanism based on 11 high-resolution X-ray structures of the 70S ribosome that explains the occurrence of missense errors during translation. We determined ribo...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rozov, Alexey, Demeshkina, Natalia, Westhof, Eric, Yusupov, Marat, Yusupova, Gulnara
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468848/
https://ncbi.nlm.nih.gov/pubmed/26037619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8251
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