Optimization of Polyene-Azole Combination Therapy against Aspergillosis Using an In Vitro Pharmacokinetic-Pharmacodynamic Model

Although amphotericin B-azole combination therapy has traditionally been questioned due to potential antagonistic interactions, it is often used successfully to treat refractory invasive aspergillosis. So far, pharmacodynamic (PD) interactions have been assessed with conventional in vitro tests, whi...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Siopi, Maria, Siafakas, Nikolaos, Vourli, Sophia, Zerva, Loukia, Meletiadis, Joseph
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468736/
https://ncbi.nlm.nih.gov/pubmed/25896699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05035-14
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