Interspecies Transfer of the Penicillin-Binding Protein 3-Encoding Gene ftsI between Haemophilus influenzae and Haemophilus haemolyticus Can Confer Reduced Susceptibility to β-Lactam Antimicrobial Agents

Mutations in ftsI, encoding penicillin-binding protein 3, can cause decreased β-lactam susceptibility in Haemophilus influenzae. Sequencing of ftsI from clinical strains has indicated interspecies recombination of ftsI between H. influenzae and Haemophilus haemolyticus. This study documented apparen...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Autores principales: Søndergaard, Annette, Witherden, Elizabeth A., Nørskov-Lauritsen, Niels, Tristram, Stephen G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468707/
https://ncbi.nlm.nih.gov/pubmed/25918135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04854-14
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