Blocking Hsp70 Enhances the Efficiency of Amphotericin B Treatment against Resistant Aspergillus terreus Strains

The polyene antifungal amphotericin B (AmB) is widely used to treat life-threatening fungal infections. Even though AmB resistance is exceptionally rare in fungi, most Aspergillus terreus isolates exhibit an intrinsic resistance against the drug in vivo and in vitro. Heat shock proteins perform a fu...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Blatzer, Michael, Blum, Gerhard, Jukic, Emina, Posch, Wilfried, Gruber, Peter, Nagl, Markus, Binder, Ulrike, Maurer, Elisabeth, Sarg, Bettina, Lindner, Herbert, Lass-Flörl, Cornelia, Wilflingseder, Doris
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468683/
https://ncbi.nlm.nih.gov/pubmed/25870060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05164-14
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