Blocking Hsp70 Enhances the Efficiency of Amphotericin B Treatment against Resistant Aspergillus terreus Strains

The polyene antifungal amphotericin B (AmB) is widely used to treat life-threatening fungal infections. Even though AmB resistance is exceptionally rare in fungi, most Aspergillus terreus isolates exhibit an intrinsic resistance against the drug in vivo and in vitro. Heat shock proteins perform a fu...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Blatzer, Michael, Blum, Gerhard, Jukic, Emina, Posch, Wilfried, Gruber, Peter, Nagl, Markus, Binder, Ulrike, Maurer, Elisabeth, Sarg, Bettina, Lindner, Herbert, Lass-Flörl, Cornelia, Wilflingseder, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468683/
https://ncbi.nlm.nih.gov/pubmed/25870060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05164-14
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