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Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neural Progenitor Cells

Human cytomegalovirus (HCMV) infection of the developing fetus frequently results in major neural developmental damage. In previous studies, HCMV was shown to downregulate neural progenitor/stem cell (NPC) markers and induce abnormal differentiation. As Notch signaling plays a vital role in the main...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Li, Xiao-Jun, Liu, Xi-Juan, Yang, Bo, Fu, Ya-Ru, Zhao, Fei, Shen, Zhang-Zhou, Miao, Ling-Feng, Rayner, Simon, Chavanas, Stéphane, Zhu, Hua, Britt, William J., Tang, Qiyi, McVoy, Michael A., Luo, Min-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468470/
https://ncbi.nlm.nih.gov/pubmed/25903338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00351-15
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