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Synoviocyte Derived-Extracellular Matrix Enhances Human Articular Chondrocyte Proliferation and Maintains Re-Differentiation Capacity at Both Low and Atmospheric Oxygen Tensions

BACKGROUND: Current tissue engineering methods are insufficient for total joint resurfacing, and chondrocytes undergo de-differentiation when expanded on tissue culture plastic. De-differentiated chondrocytes show poor re-differentiation in culture, giving reduced glycosaminoglycan (GAG) and collage...

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Foilsithe in:PLoS One
Main Authors: Kean, Thomas J., Dennis, James E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468209/
https://ncbi.nlm.nih.gov/pubmed/26075742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129961
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