Mitochondrial DNA sequence variation in human evolution and disease.
Germ-line and somatic mtDNA mutations are hypothesized to act together to shape our history and our health. Germ-line mtDNA mutations, both ancient and recent, have been associated with a variety of degenerative diseases. Mildly to moderately deleterious germ-line mutations, like neutral polymorphis...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44682/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8090716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.19.8739 |
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