Intra-Arterial Transplantation of Allogeneic Mesenchymal Stem Cells Mounts Neuroprotective Effects in a Transient Ischemic Stroke Model in Rats: Analyses of Therapeutic Time Window and Its Mechanisms

OBJECTIVE: Intra-arterial stem cell transplantation exerts neuroprotective effects for ischemic stroke. However, the optimal therapeutic time window and mechanisms have not been completely understood. In this study, we investigated the relationship between the timing of intra-arterial transplantatio...

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Veröffentlicht in:PLoS One
Hauptverfasser: Toyoshima, Atsuhiko, Yasuhara, Takao, Kameda, Masahiro, Morimoto, Jun, Takeuchi, Hayato, Wang, Feifei, Sasaki, Tatsuya, Sasada, Susumu, Shinko, Aiko, Wakamori, Takaaki, Okazaki, Mihoko, Kondo, Akihiko, Agari, Takashi, Borlongan, Cesario V., Date, Isao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468176/
https://ncbi.nlm.nih.gov/pubmed/26075717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127302
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