2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline

Heparan sulfate (HS) is a linear carbohydrate composed of polymerized uronate-glucosamine disaccharide units that decorates cell surface and secreted glycoproteins in the extracellular matrix. In mammals HS is subjected to differential sulfation by fifteen different heparan sulfotransferase (HST) en...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chan, Wai Kit, Howe, Katherine, Clegg, James M., Guimond, Scott E., Price, David J., Turnbull, Jeremy E., Pratt, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468130/
https://ncbi.nlm.nih.gov/pubmed/26075383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130147
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