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Combination Treatment with All-Trans Retinoic Acid Prevents Cisplatin-Induced Enrichment of CD133(+) Tumor-Initiating Cells and Reveals Heterogeneity of Cancer Stem Cell Compartment in Lung Cancer
The existence of specific cellular subpopulations within primary tumors with increased tumorigenic potential and chemotherapy resistance (tumor-initiating cells, TICs) holds great therapeutic implications. Resistant cells can remain quiescent for long periods and be responsible for local relapses an...
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| Publicado en: | J Thorac Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Lippincott Williams & Wilkins
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4467987/ https://ncbi.nlm.nih.gov/pubmed/26020124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000563 |
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