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Sleep disorders, obesity, and aging: the role of orexin

The hypothalamic neuropeptides orexin A and B (hypocretin 1 and 2) are important homeostatic mediators of central control of energy metabolism and maintenance of sleep/wake states. Dysregulation or loss of orexin signaling has been linked to narcolepsy, obesity, and age-related disorders. In this re...

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Detalhes bibliográficos
Publicado no:Ageing Res Rev
Main Authors: Nixon, Joshua P., Mavanji, Vijayakumar, Butterick, Tammy A., Billington, Charles J., Kotz, Catherine M., Teske, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467809/
https://ncbi.nlm.nih.gov/pubmed/25462194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2014.11.001
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