Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B

BACKGROUND: Activins are members of the TGF-β family of ligands that have multiple biological functions in embryonic stem cells as well as in differentiated tissue. Serum levels of activin A were found to be elevated in pathological conditions such as cachexia, osteoporosis and cancer. Signaling by...

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Publicat a:Cell Commun Signal
Autors principals: Olsen, Oddrun Elise, Wader, Karin Fahl, Hella, Hanne, Mylin, Anne Kærsgaard, Turesson, Ingemar, Nesthus, Ingerid, Waage, Anders, Sundan, Anders, Holien, Toril
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467681/
https://ncbi.nlm.nih.gov/pubmed/26047946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0104-z
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