Anti-dsDNA antibodies induce inflammation via endoplasmic reticulum stress in human mesangial cells

BACKGROUND: Anti-dsDNA antibodies play an important role in the pathogenesis of lupus nephritis (LN). Endoplasmic reticulum (ER) stress is a physical reaction under stressful condition and can cause inflammation when stimulation is sustained. This study investigated the roles of ER stress in anti-ds...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Zhang, Hui, Zhao, Chunmei, Wang, Shuang, Huang, Yuefang, Wang, Hongyue, Zhao, Jijun, Yang, Niansheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467615/
https://ncbi.nlm.nih.gov/pubmed/26040555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0536-7
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