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Increased Programmed Death-1 Expression on CD4(+) T Cells in Cutaneous T-Cell Lymphoma: Implications for Immune Suppression

OBJECTIVES: To investigate the expression profile of programmed death-1 (PD-1) on T cells derived from patients with cutaneous T-cell lymphoma (CTCL), analyze a potential mechanism responsible for upregulation of PD-1, and assess the correlation between blockade of its signaling pathway and improvem...

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Détails bibliographiques
Publié dans:Arch Dermatol
Auteurs principaux: Samimi, Sara, Benoit, Bernice, Evans, Katherine, Wherry, E. John, Showe, Louise, Wysocka, Maria, Rook, Alain H.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467572/
https://ncbi.nlm.nih.gov/pubmed/20713771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archdermatol.2010.200
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