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Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFκB signaling

Regulatory mechanisms underlying constitutive and inducible NFκB activation in cancer remain largely unknown. Here we investigated whether a novel NIK- and IKK2-binding protein (NIBP) is required for maintaining malignancy of cancer cells in an NFκB-dependent manner. Real-time polymerase chain react...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Zhang, Yonggang, Liu, Shu, Wang, Hong, Yang, Wensheng, Li, Fang, Yang, Fan, Yu, Daohai, Ramsey, Frederick V., Tuszyski, George P., Hu, Wenhui
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467429/
https://ncbi.nlm.nih.gov/pubmed/25704885
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