New insights into the genetics of glioblastoma multiforme by familial exome sequencing

Glioblastoma multiforme (GBM) is the most aggressive and malignant subtype of human brain tumors. While a family clustering of GBM has long been acknowledged, relevant hereditary factors still remained elusive. Exome sequencing of families offers the option to discover respective genetic factors. We...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Backes, Christina, Harz, Christian, Fischer, Ulrike, Schmitt, Jana, Ludwig, Nicole, Petersen, Britt-Sabina, Mueller, Sabine C., Kim, Yoo-Jin, Wolf, Nadine M., Katus, Hugo A., Meder, Benjamin, Furtwängler, Rhoikos, Franke, Andre, Bohle, Rainer, Henn, Wolfram, Graf, Norbert, Keller, Andreas, Meese, Eckart
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467411/
https://ncbi.nlm.nih.gov/pubmed/25537509
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