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Expression of the tumor suppressor gene hypermethylated in cancer 1 in laryngeal carcinoma
Hypermethylated in cancer 1 (HIC1) is a putative suppressor gene, cooperating with TP53 in the regulation of apoptosis. The promoter site of this gene contains CpG islands susceptible to methylation. Altered methylation leads to the silencing of HIC1. Persistent loss of HIC1 function reflects the at...
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| Publicado no: | Oncol Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4467338/ https://ncbi.nlm.nih.gov/pubmed/26137060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.2983 |
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