PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migration

PATZ1, a POZ-Zinc finger protein, is emerging as an important regulator of development and cancer, but its cancer-related function as oncogene or tumor-suppressor is still debated. Here, we investigated its possible role in thyroid carcinogenesis. We demonstrated PATZ1 is down-regulated in thyroid c...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chiappetta, Gennaro, Valentino, Teresa, Vitiello, Michela, Pasquinelli, Rosa, Monaco, Mario, Palma, Giuseppe, Sepe, Romina, Luciano, Antonio, Pallante, Pierlorenzo, Palmieri, Dario, Aiello, Concetta, Rea, Domenica, Losito, Simona Nunzia, Arra, Claudio, Fusco, Alfredo, Fedele, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467151/
https://ncbi.nlm.nih.gov/pubmed/25595894
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