FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells

Triple negative breast cancer (TNBC) is a highly metastatic disease that currently lacks effective prevention and treatment strategies. The insulin-like growth factor 1 receptor (IGF1R) and focal adhesion kinase (FAK) signaling pathways function in numerous developmental processes, and alterations i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Taliaferro-Smith, LaTonia, Oberlick, Elaine, Liu, Tongrui, McGlothen, Tanisha, Alcaide, Tiffanie, Tobin, Rachel, Donnelly, Siobhan, Commander, Rachel, Kline, Erik, Nagaraju, Ganji Purnachandra, Havel, Lauren, Marcus, Adam, Nahta, Rita, O'Regan, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467113/
https://ncbi.nlm.nih.gov/pubmed/25749031
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