Stromal-derived factor-1α/CXCL12-CXCR4 chemotactic pathway promotes perineural invasion in pancreatic cancer

Perineural invasion (PNI) is considered as an alternative route for the metastatic spread of pancreatic cancer cells; however, the molecular changes leading to PNI are still poorly understood. In this study, we show that the CXCL12/CXCR4 axis plays a pivotal role in the neurotropism of pancreatic ca...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Xu, Qinhong, Wang, Zheng, Chen, Xin, Duan, Wanxing, Lei, Jianjun, Zong, Liang, Li, Xuqi, Sheng, Liang, Ma, Jiguang, Han, Liang, Li, Wei, Zhang, Lun, Guo, Kun, Ma, Zhenhua, Wu, Zheng, Wu, Erxi, Ma, Qingyong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467110/
https://ncbi.nlm.nih.gov/pubmed/25605248
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