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Production and characterization of thirteen human Type-I interferon-α subtypes

Thirteen human interferon-α (IFNα) subtypes were expressed in E. coli and purified using an N-terminal affinity tag from the prodomain of subtilisn. IFNα subtypes were expressed in soluble form and purified from cell lysates or refolded and purified from inclusion bodies. Proteins produced by either...

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Detalhes bibliográficos
Publicado no:Protein Expr Purif
Main Authors: Kuruganti, Srilalitha, Accavitti-Loper, Mary Ann, Walter, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466898/
https://ncbi.nlm.nih.gov/pubmed/25149396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2014.08.010
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