The effect of BIM deletion polymorphism on intrinsic resistance and clinical outcome of cancer patient with kinase inhibitor therapy

A common deletion polymorphism within B-cell chronic lymphocytic leukemia-lymphoma like 11 gene (BIM) was deemed to be a genetic cause leading to compromised kinase inhibitor therapeutic efficacy in cancer individuals. However, the results reported were not consistent. Thus, a comprehensive meta-ana...

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Publicado no:Sci Rep
Main Authors: Ying, Hou-Qun, Chen, Jie, He, Bang-Shun, Pan, Yu-Qin, Wang, Feng, Deng, Qi-Wen, Sun, Hui-Ling, Liu, Xian, Wang, Shu-Kui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466895/
https://ncbi.nlm.nih.gov/pubmed/26076815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11348
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