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Reduced endogenous Ca(2+) buffering speeds active zone Ca(2+) signaling

Fast synchronous neurotransmitter release at the presynaptic active zone is triggered by local Ca(2+) signals, which are confined in their spatiotemporal extent by endogenous Ca(2+) buffers. However, it remains elusive how rapid and reliable Ca(2+) signaling can be sustained during repetitive releas...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Delvendahl, Igor, Jablonski, Lukasz, Baade, Carolin, Matveev, Victor, Neher, Erwin, Hallermann, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466756/
https://ncbi.nlm.nih.gov/pubmed/26015575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508419112
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