The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

P granules and other RNA/protein bodies are membrane-less organelles that may assemble by intracellular phase separation, similar to the condensation of water vapor into droplets. However, the molecular driving forces and the nature of the condensed phases remain poorly understood. Here, we show tha...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Elbaum-Garfinkle, Shana, Kim, Younghoon, Szczepaniak, Krzysztof, Chen, Carlos Chih-Hsiung, Eckmann, Christian R., Myong, Sua, Brangwynne, Clifford P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466716/
https://ncbi.nlm.nih.gov/pubmed/26015579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504822112
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