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Transcriptome-wide identification and study of cancer-specific splicing events across multiple tumors

Dysregulation of alternative splicing (AS) is one of the molecular hallmarks of cancer, with splicing alteration of numerous genes in cancer patients. However, studying splicing mis-regulation in cancer is complicated by the large noise generated from tissue-specific splicing. To obtain a global pic...

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Publicat a:Oncotarget
Autors principals: Tsai, Yihsuan S., Dominguez, Daniel, Gomez, Shawn M., Wang, Zefeng
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466652/
https://ncbi.nlm.nih.gov/pubmed/25749525
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