Trisomy 8, a Cytogenetic Abnormality in Myelodysplastic Syndromes, Is Constitutional or Not?

Isolated trisomy 8 is not considered presumptive evidence of myelodysplastic syndrome (MDS) in cases without minimal morphological criteria. One reason given is that trisomy 8 (+8) can be found as a constitutional mosaicism (cT8M). We tried to clarify the incidence of cT8M in myeloid neoplasms, spec...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Saumell, Sílvia, Solé, Francesc, Arenillas, Leonor, Montoro, Julia, Valcárcel, David, Pedro, Carme, Sanzo, Carmen, Luño, Elisa, Giménez, Teresa, Arnan, Montserrat, Pomares, Helena, De Paz, Raquel, Arrizabalaga, Beatriz, Jerez, Andrés, Martínez, Ana B., Sánchez-Castro, Judith, Rodríguez-Gambarte, Juan D., Raya, José M., Ríos, Eduardo, Rodríguez-Rivera, María, Espinet, Blanca, Florensa, Lourdes
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466575/
https://ncbi.nlm.nih.gov/pubmed/26066831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129375
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