Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice

INTRODUCTION: Airway surface dehydration, caused by an imbalance between secretion and absorption of ions and fluid across the epithelium and/or increased epithelial mucin secretion, impairs mucociliary clearance. Recent evidence suggests that this mechanism may be implicated in chronic obstructive...

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Publicado en:PLoS One
Autores principales: Seys, Leen J. M., Verhamme, Fien M., Dupont, Lisa L., Desauter, Elke, Duerr, Julia, Seyhan Agircan, Ayca, Conickx, Griet, Joos, Guy F., Brusselle, Guy G., Mall, Marcus A., Bracke, Ken R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466573/
https://ncbi.nlm.nih.gov/pubmed/26066648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129897
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