Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice

INTRODUCTION: Airway surface dehydration, caused by an imbalance between secretion and absorption of ions and fluid across the epithelium and/or increased epithelial mucin secretion, impairs mucociliary clearance. Recent evidence suggests that this mechanism may be implicated in chronic obstructive...

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Bibliographic Details
Published in:PLoS One
Main Authors: Seys, Leen J. M., Verhamme, Fien M., Dupont, Lisa L., Desauter, Elke, Duerr, Julia, Seyhan Agircan, Ayca, Conickx, Griet, Joos, Guy F., Brusselle, Guy G., Mall, Marcus A., Bracke, Ken R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466573/
https://ncbi.nlm.nih.gov/pubmed/26066648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129897
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