Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice

INTRODUCTION: Airway surface dehydration, caused by an imbalance between secretion and absorption of ions and fluid across the epithelium and/or increased epithelial mucin secretion, impairs mucociliary clearance. Recent evidence suggests that this mechanism may be implicated in chronic obstructive...

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Veröffentlicht in:PLoS One
Hauptverfasser: Seys, Leen J. M., Verhamme, Fien M., Dupont, Lisa L., Desauter, Elke, Duerr, Julia, Seyhan Agircan, Ayca, Conickx, Griet, Joos, Guy F., Brusselle, Guy G., Mall, Marcus A., Bracke, Ken R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466573/
https://ncbi.nlm.nih.gov/pubmed/26066648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129897
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