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PERK-mediated Autophagy in Osteosarcoma Cells Resists ER Stress-induced Cell Apoptosis
Osteosarcoma is a bone cancer that develops commonly in children and adolescents. However, osteosarcoma treatments often fail by the development of chemoresistance to apoptosis, and the molecular mechanisms remain unclear. In this study, we propose that autophagy is responsible for osteosarcomatous...
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| Publicado no: | Int J Biol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4466461/ https://ncbi.nlm.nih.gov/pubmed/26078722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.11100 |
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