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Mitochondrial function, zinc, and intermediary metabolism relationships in normal prostate and prostate cancer

Human prostate secretory epithelial cells have the uniquely specialized function of accumulating and secreting extremely high levels of citrate. This is achieved by their ability to accumulate high cellular levels of zinc that inhibit citrate oxidation. This process of net citrate production require...

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Bibliographic Details
Published in:Mitochondrion
Main Authors: Costello, L.C., Franklin, R.B., Feng, Pei
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466120/
https://ncbi.nlm.nih.gov/pubmed/16050980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2005.02.001
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