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Colonic insult impairs lymph flow, increases cellular content of the lymph, alters local lymphatic micro-environment and leads to sustained inflammation in the rat ileum

BACKGROUND: Lymphatic dysfunction has been linked to inflammation since the 1930’s. Lymphatic function in the gut and mesentery is grossly underexplored in models of IBD despite the use of lymphatic occlusion in early models of IBD. Activation of the innate and adaptive immune system is a hallmark o...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Cromer, Walter, Wang, Wei, Zawieja, Scott D., von der Weid, Pierre-Yves, Newell Rogers, M. Karen, Zawieja, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466086/
https://ncbi.nlm.nih.gov/pubmed/25939039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000402
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