Quantitative pharmacokinetic analysis of prostate cancer DCE-MRI at 3T: Comparison of two arterial input functions on cancer detection with digitized whole mount histopathological validation

Accurate pharmacokinetic (PK) modeling of Dynamic Contrast Enhanced MRI (DCE-MRI) in prostate cancer requires knowledge of the concentration time course of the contrast agent in the feeding vasculature, the so-called arterial input function (AIF). The purpose of this study was to compare AIF choice...

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Detalhes bibliográficos
Publicado no:Magn Reson Imaging
Main Authors: Fennessy, Fiona M., Fedorov, Andriy, Penzkofer, Tobias, Kim, Kyung Won, Hirsch, Michelle S, Vangel, Mark G., Masry, Paul, Flood, Trevor A., Chang, Ming-Ching, Tempany, Clare M., Mulkern, Robert V., Gupta, Sandeep N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465997/
https://ncbi.nlm.nih.gov/pubmed/25683515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mri.2015.02.008
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