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Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells

The common pathogen Epstein-Barr virus (EBV) transforms normal human B cells and can cause cancer. Latent membrane protein 2A (LMP2A) of EBV supports activation and proliferation of infected B cells and is expressed in many types of EBV-associated cancer. It is not clear how latent EBV infection and...

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Publicat a:PLoS Pathog
Autors principals: Rancan, Chiara, Schirrmann, Leah, Hüls, Corinna, Zeidler, Reinhard, Moosmann, Andreas
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465838/
https://ncbi.nlm.nih.gov/pubmed/26067064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004906
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