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Mouse liver-specific CD8(+) T cells encounter their cognate antigen and acquire capacity to destroy target hepatocytes
CD8(+) T-cell immune response to liver antigens is often functionally diminished or absent. This may occur via deletion of these autoaggressive T cells, through the acquisition of an anergic phenotype, or via active suppression mediated by other cell populations. We generated a double transgenic mod...
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| Publicado no: | J Autoimmun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4465814/ https://ncbi.nlm.nih.gov/pubmed/23137675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2012.10.002 |
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