Lipopolysaccharide-Induced Human Enterocyte Tolerance to Cytokine-Mediated Interleukin-8 Production May Occur Independently of TLR-4/MD-2 Signaling

Intestinal epithelial cells (IEC) are constantly exposed to bacterial components, such as LPS, without triggering proinflammatory immune responses. This study demonstrates that chronic exposure of human-derived IEC to LPS induces tolerance to an endogenous inflammatory cytokine (IL-1β) activated IL-...

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Bibliografiska uppgifter
I publikationen:Pediatr Res
Huvudupphovsmän: SAVIDGE, TOR C., NEWMAN, PAUL G., PAN, WEI-HUA, WENG, MEI-QIAN, SHI, HAI NING, MCCORMICK, BETH A., QUARONI, ANDREA, WALKER, W. ALLAN
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2005
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465784/
https://ncbi.nlm.nih.gov/pubmed/16326999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/01.pdr.0000195101.74184.e3
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