Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe

Eukaryotic genomes are folded into three-dimensional structures, such as self-associating topological domains, the borders of which are enriched in cohesin and CCCTC-binding factor (CTCF) required for long-range interactions(1-7). How local chromatin interactions govern higher-order folding of chrom...

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Bibliographic Details
Published in:Nature
Main Authors: Mizuguchi, Takeshi, Fudenberg, Geoffrey, Mehta, Sameet, Belton, Jon-Matthew, Taneja, Nitika, Folco, Hernan Diego, FitzGerald, Peter, Dekker, Job, Mirny, Leonid, Barrowman, Jemima, Grewal, Shiv I. S.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465753/
https://ncbi.nlm.nih.gov/pubmed/25307058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13833
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