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Attacking the Multi-tiered Proteolytic Pathology of COPD: New Insights from Basic and Translational Studies
Protease activity in inflammation is complex. Proteases released by cells in response to infection, cytokines, or environmental triggers like cigarette smoking cause breakdown of the extracellular matrix (ECM). In chronic inflammatory diseases like chronic obstructive pulmonary disease (COPD), curre...
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Publicado no: | Pharmacol Ther |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4465592/ https://ncbi.nlm.nih.gov/pubmed/19026684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2008.09.008 |
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