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Attacking the Multi-tiered Proteolytic Pathology of COPD: New Insights from Basic and Translational Studies

Protease activity in inflammation is complex. Proteases released by cells in response to infection, cytokines, or environmental triggers like cigarette smoking cause breakdown of the extracellular matrix (ECM). In chronic inflammatory diseases like chronic obstructive pulmonary disease (COPD), curre...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Djekic, Uros V, Gaggar, Amit, Weathington, Nathaniel M
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465592/
https://ncbi.nlm.nih.gov/pubmed/19026684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2008.09.008
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