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Peptide Decoration of Nanovehicles to Achieve Active Targeting and Pathology-Responsive Cellular Uptake for Bone Metastasis Chemotherapy

To improve bone metastases chemotherapy, a peptide-conjugated diblock copolymer consisting of chimeric peptide, poly(ethylene glycol) and poly(trimethylene carbonate) (Pep-b-PEG-b-PTMC) is fabricated as a drug carrier capable of bone-seeking targeting as well as pathology-responsive charge reversal...

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Detalhes bibliográficos
Publicado no:Biomater Sci
Main Authors: Wang, Xuli, Yang, Ye, Jia, Huizhen, Jia, Wanjian, Miller, Scott, Bowman, Beth, Feng, Jun, Zhan, Fenghuang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465575/
https://ncbi.nlm.nih.gov/pubmed/26082834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4BM00020J
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