Development of a novel IGRA assay to test T cell responsiveness to HBV antigens in whole blood of chronic Hepatitis B patients

BACKGROUND: Interferon gamma release assays (IGRA) have been developed to support easy and fast diagnosis of diseases like tuberculosis, and CMV in transplant patients. IGRAs focus on cellular immunity especially memory T cells and thus also allow rapid screening prior to complex flow cytometric tes...

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Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Dammermann, Werner, Bentzien, Frank, Stiel, Eva-Maria, Kühne, Claudia, Ullrich, Sebastian, zur Wiesch, Julian Schulze, Lüth, Stefan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465460/
https://ncbi.nlm.nih.gov/pubmed/25968473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0513-1
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