Lysophosphatidic Acid Mediates Fibrosis In Injured Joints By Regulating Collagen Type I Biosynthesis

OBJECTIVE: Articular cartilage is a highly specialized tissue which forms the surfaces in synovial joints. Full-thickness cartilage defects caused by trauma or microfracture surgery heal via the formation of fibrotic tissue characterized by a high content of collagen I (COL I) and subsequent poor me...

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Detalhes bibliográficos
Publicado no:Osteoarthritis Cartilage
Main Authors: Wu, Ling, Petrigliano, Frank A., Ba, Kai, Lee, Siyoung, Bogdanov, Jacob, McAllister, David R., Adams, John S, Rosenthal, Ann K, Van Handel, Ben, Crooks, Gay M, Lin, Yunfeng, Evseenko, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465392/
https://ncbi.nlm.nih.gov/pubmed/25464168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2014.11.012
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