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Cytoplasmic dynein is required for the spatial organization of protein aggregates in filamentous fungi

Eukaryotes have evolved multiple strategies for maintaining cellular protein homeostasis. One such mechanism involves neutralization of deleterious protein aggregates via their defined spatial segregation. Here, using the molecular disaggregase Hsp104 as a marker for protein aggregation, we describe...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Egan, Martin J., McClintock, Mark A., Hollyer, Ian H. L., Elliott, Hunter L., Reck-Peterson, Samara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465048/
https://ncbi.nlm.nih.gov/pubmed/25865884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.028
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