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High-Resolution Survey in Familial Parkinson Disease Genes Reveals Multiple Independent Copy Number Variation Events in PARK2

A high density comparative genomic hybridization array was designed to evaluate CNVs in the genomic region of six familial PD genes in 181 PD cases and 67 controls. No CNV was found in PARK7, ATP13A2, PINK1, and LRRK2. Intronic-only CNVs were found in SNCA and PARK2 but were not associated with PD r...

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Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Wang, Liyong, Nuytemans, Karen, Bademci, Guney, Jauregui, Cherylyn, Martin, Eden R., Scott, William K., Vance, Jeffery M., Zuchner, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464794/
https://ncbi.nlm.nih.gov/pubmed/23616242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22344
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