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Effects of hypoxia inducible factor-1α on apoptotic inhibition and glucocorticoid receptor downregulation by dexamethasone in AtT-20 cells

BACKGROUND: Hypoxia inducible factor-1α (HIF-1α) is the central transcriptional regulator of hypoxic responses during the progression of pituitary adenomas. Although previous immunohistochemical studies revealed that HIF-1α is expressed in adreno-cortico-tropic-hormone (ACTH) pituitary adenomas, the...

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Detalhes bibliográficos
Publicado no:BMC Endocr Disord
Main Authors: Zhang, Chenran, Qiang, Qiang, Jiang, Ying, Hu, Liuhua, Ding, Xuehua, Lu, Yicheng, Hu, Guohan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464719/
https://ncbi.nlm.nih.gov/pubmed/26002039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12902-015-0017-2
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