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Tissue-Specific Patterning of Host Innate Immune Responses by Staphylococcus aureus α-Toxin

Immunomodulatory cytotoxins are prominent virulence factors produced by Staphylococcus aureus, a leading cause of bacterial sepsis, skin infection, and pneumonia. S. aureus α-toxin is a pore-forming toxin that utilizes a widely expressed receptor, ADAM10, to injure the host epithelium, endothelium,...

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Foilsithe in:J Innate Immun
Main Authors: Becker, Russell E.N., Berube, Bryan J., Sampedro, Georgia R., DeDent, Andrea C., Bubeck Wardenburg, Juliane
Formáid: Artigo
Teanga:Inglês
Foilsithe: S. Karger AG 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464663/
https://ncbi.nlm.nih.gov/pubmed/24820433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000360006
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