Chronic social stress impairs virus specific adaptive immunity during acute Theiler’s virus infection

Prior exposure to social disruption (SDR) stress exacerbates Theiler’s murine encephalomyelitis virus (TMEV) infection, a model of multiple sclerosis. Here we examined the impact of SDR on T cell responses to TMEV infection in SJL mice. SDR impaired viral clearance and exacerbated acute disease. Mor...

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Detalhes bibliográficos
Publicado no:J Neuroimmunol
Main Authors: Young, Erin E., Vichaya, Elisabeth G., Reusser, Nicole M., Cook, Jennifer L., Steelman, Andrew R., Welsh, C. Jane R., Meagher, Mary W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464662/
https://ncbi.nlm.nih.gov/pubmed/23021485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2012.08.014
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