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Synthesis of multivalent carbohydrate mimetics with aminopolyol end groups and their evaluation as L-selectin inhibitors

In this article a series of divalent and trivalent carbohydrate mimetics on the basis of an enantiopure aminopyran and of serinol is described. These aminopolyols are connected by amide bonds to carboxylic acid derived spacer units either by Schotten–Baumann acylation or by coupling employing HATU a...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Salta, Joana, Dernedde, Jens, Reissig, Hans-Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464473/
https://ncbi.nlm.nih.gov/pubmed/26124866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.72
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