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Downregulation of Sprouty homolog 2 by microRNA-21 inhibits proliferation, metastasis and invasion, however promotes the apoptosis of multiple myeloma cells

The aim of the present study was to assess the effects of sprouty homolog 2 (SPRY2) gene regulation by miR-21 on the occurrence, development and tumor metastasis in multiple myeloma (MM). The miR-21 expression lentiviral vector (LV)-anti-miR-21 and a liposome transfection method were used to screen...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: WANG, JIN-HANG, ZHOU, WEN-WEN, CHENG, SHI-TONG, LIU, BO-XIN, LIU, FU-RONG, SONG, JIAN-QING
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464399/
https://ncbi.nlm.nih.gov/pubmed/25825239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.3567
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